Differences between CT Scan and PET Scan
Computed Tomography (CT) Scan vs. Positron Emission Tomography (PET) Scan
Computed tomography (CT) and positron emission tomography (PET) are both medical imaging techniques used to create detailed pictures of the inside of the body.[1][2] While both are noninvasive procedures, they work in fundamentally different ways and provide distinct types of information.[3][1] A CT scan focuses on anatomy and structure, whereas a PET scan assesses metabolic processes and the function of organs and tissues on a cellular level.[4][5]
A CT scanner takes a series of X-ray images from many different angles around the body. A computer then processes these images to create cross-sectional "slices" of bones, organs, and soft tissues. These slices can be combined to form a three-dimensional image, offering a more detailed view than a standard X-ray. CT scans are widely used to diagnose and monitor a variety of conditions, including bone fractures, internal bleeding, blood clots, and cancer. The procedure is relatively quick, often completed within minutes.[3]
A PET scan is a type of nuclear medicine imaging that shows how organs and tissues are functioning. Before the scan, the patient receives an injection of a radioactive tracer, most commonly a form of radioactive glucose called fluorodeoxyglucose (FDG). This tracer travels through the bloodstream and is absorbed by the body's cells. Tissues that are more metabolically active, such as cancer cells, absorb more of the tracer and appear as bright spots on the resulting images. This allows PET scans to detect biochemical changes associated with disease, sometimes before anatomical changes are visible on other imaging tests. In addition to oncology, PET scans are used in neurology to evaluate conditions like Alzheimer's disease and epilepsy, and in cardiology to assess blood flow to the heart muscle. The entire process, including the time for the tracer to be absorbed, can take from 30 minutes to a few hours.[4]
Often, CT and PET scans are used together in a hybrid imaging machine known as a PET-CT scanner. This combination allows for the functional information from the PET scan to be superimposed on the detailed anatomical images from the CT scan, providing a more complete and accurate picture for diagnosis and treatment planning.
Comparison Table
| Category | CT Scan | PET Scan |
|---|---|---|
| Primary Function | Provides detailed anatomical images of structures inside the body.[4] | Shows the metabolic activity and function of tissues and organs.[4] |
| Technology | Uses a series of X-ray beams taken from multiple angles. | Detects radiation from an injected radioactive tracer. |
| Information Provided | Structural (Anatomy) | Functional (Metabolic activity) |
| Agent Used | Sometimes uses a contrast dye (oral or intravenous) to enhance images. | Uses a radioactive tracer (e.g., FDG) injected into a vein. |
| Common Applications | Detecting injuries, bone fractures, tumors, internal bleeding, and blood clots. | Detecting cancer, assessing cancer treatment, evaluating brain disorders (e.g., dementia, epilepsy), and heart conditions. |
| Speed of Scan | Typically fast, often lasting only a few minutes.[3] | Longer procedure, including about an hour for tracer absorption, with the scan itself taking 30-45 minutes.[3] |
| Radiation Source | External radiation from a rotating X-ray machine. | Internal radiation from the injected radioactive tracer.[3] |
References
- ↑ 1.0 1.1 "verywellhealth.com". Retrieved January 20, 2026.
- ↑ "mayoclinic.org". Retrieved January 20, 2026.
- ↑ 3.0 3.1 3.2 3.3 3.4 "healthimages.com". Retrieved January 20, 2026.
- ↑ 4.0 4.1 4.2 4.3 "livhospital.com". Retrieved January 20, 2026.
- ↑ "mdanderson.org". Retrieved January 20, 2026.
