Differences between Anabolism and Catabolism

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Anabolism vs. Catabolism

Anabolism and catabolism are the two categories of chemical reactions that make up metabolism.[1] Anabolism refers to constructive metabolic processes. These reactions use energy to build complex molecules from simpler ones, such as proteins from amino acids or polysaccharides from monosaccharides.[2] Catabolism is the opposite process, where complex molecules are broken down into smaller ones, which releases energy.[3][1] Together, these two processes manage the flow of energy and materials that allow organisms to grow, maintain their structures, and respond to their environments.[1]

The energy released by catabolic pathways is temporarily stored in the bonds of adenosine triphosphate (ATP), which acts as the primary energy currency of the cell.[4][1] Anabolic reactions then consume this ATP to power the synthesis of new molecules and cellular structures.[4][1] The balance between anabolic and catabolic rates is regulated by hormones.[2] Anabolic hormones include insulin, testosterone, and growth hormone, while catabolic hormones include cortisol, glucagon, and adrenaline.[5]

Comparison table

Feature Anabolism Catabolism
Process Type Synthesis (builds up) Decomposition (breaks down)
Molecule Size Converts simple molecules into complex ones[2] Breaks down complex molecules into simple ones
Energy Flow Requires energy input (endergonic)[4] Releases energy (exergonic)[4]
Energy Source/Product Consumes ATP Produces ATP
Primary Function Growth, repair, and storage of energy Release of energy and production of components for anabolic reactions[1]
Regulating Hormones Insulin, estrogen, testosterone, growth hormone[5][2] Cortisol, glucagon, adrenaline, cytokines[5][2]
Example Pathways Protein synthesis, gluconeogenesis, glycogen synthesis[5] Digestion, glycolysis, breakdown of proteins into amino acids[5]
Venn diagram for Differences between Anabolism and Catabolism
Venn diagram comparing Differences between Anabolism and Catabolism


Relationship in exercise

Physical exercise involves both anabolic and catabolic processes. Activities like running, swimming, and cycling are primarily catabolic, as they break down glucose and fat to release large amounts of energy to fuel the activity. In contrast, anaerobic exercises like weightlifting are considered anabolic. While they require energy, their main effect is to cause small tears in muscle fibers, which the body then repairs and rebuilds stronger than before, a process that consumes energy to build new tissue. A combination of both types of exercise is often used for managing body weight, as catabolic workouts burn calories during the activity, while anabolic workouts can increase muscle mass, which uses more calories over a longer period for muscle repair and maintenance.


References

  1. 1.0 1.1 1.2 1.3 1.4 1.5 "wikipedia.org". Retrieved December 05, 2025.
  2. 2.0 2.1 2.2 2.3 2.4 "lumenlearning.com". Retrieved December 05, 2025.
  3. "cellgs.com". Retrieved December 05, 2025.
  4. 4.0 4.1 4.2 4.3 "pressbooks.pub". Retrieved December 05, 2025.
  5. 5.0 5.1 5.2 5.3 5.4 "healthline.com". Retrieved December 05, 2025.